Naltrexone is not a new drug, but when used off-label at very low doses, is a drug shown in many trials to be of therapeutic benefit. The 50mg dose of Naltrexone was approved by the FDA in 1984 to treat opioid and alcohol addiction. In 1985,
Bernard Bihari, MD, a physician in New York, discovered the effects of a much smaller dose of Naltrexone. When reduced to doses ranging from 0.5mg to 9.0mg daily, it can modulate the immune system and may provide relief to those suffering from autoimmune diseases, chronic pain, mental health challenges, and inflammation.
Understanding how LDN works requires a grasp of three fundamental biological principles. First, opiate receptors are present in multiple biological systems in the human body, as they regulate a great number of biological functions via the central release of natural opiates (endorphins/met-enkephalins). Second, a class of proteins called toll-like receptors (TLRs) are part of the immune system, providing a first line of defense against microbial invasion and possessing the ability to recognize and be activated by not only pathogens but also endogenous signaling molecules. Lastly, LDN has antagonistic activity in both of these areas and is able to modify biological functions of these receptor groups by suppressing unwanted immune reactions or by stimulating disease-suppressed immune activity.
We have seen a wide variety of LDN successes. It is these successes that motivate us to continue to try to help other patients.
We are excited to share LDN with you for four main reasons: it’s safe, it has few side effects, it’s cost effective (about $1/day), and it works for patients with many different conditions.
LDN is available only by prescription and is custom made at a compounding pharmacy. The key to success in using LDN is an understanding that optimal dosing is ultimately patient specific and is not dependent on a set protocol. Dosing strategies can vary tremendously. Some patients find success very quickly, while others need to adjust their dosing strategy and may take up to several months to achieve success. Therefore, it is critical to work with a provider or a compounding pharmacy knowledgeable in strategies that can help ensure success with LDN.
We have been specializing in and making LDN in our accredited compounding lab for many years. If you would like to know more, visit our website or stop by the pharmacy. We can even provide you information to take to your physician.
*These statements are culmination of the knowledge and experience of the team at Norland Pharmacy. The information provided here is for informational purposes only. Please consult your healthcare provider with questions concerning any medical condition or treatment. Compounded medications are not reviewed by the FDA for safety or efficacy. These statements have not been evaluated by the Food and Drug Administration, and this product is not intended to diagnose, treat, cure or prevent any disease.
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